Evidence based sperm DNA fragmentation

Evidence based sperm DNA fragmentation

Evidence-based application of sperm DNA fragmentation testing

Very few disciplines of medicine have undergone significant and radical advances as reproductive medicine. Male infertility evaluation and treatment, only three decades ago, was in its most primitive form. With the introduction of ICSI, the treatment of male infertility has been revolutionized. However, the understanding and in depth evaluation of this disease has lagged behind the technical ad...

Sperm DNA fragmentation

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. It is an honour to write the foreword to this focused issue of TAU on sperm DNA fragmentation (SDF). From my time as a first generation embryologist in the early days at the University of Cambridge with Professor Robert Edwards and in my current role at the London Women’s Clinic, I have become acutely aware of the num...

Sperm DNA fragmentation testing

The editors of this book, Drs. Ashok Agarwal, Ahmad Majzoub, Chak-Lam Cho and Sandro Esteves, are to be congratulated for bringing together an extensive tome on the evaluation and management of sperm DNA fragmentation. The perspectives from North America, South America, Europe, Asia and the rest of the world provide an interesting snapshot into management of the unique phenomenon of sperm DNA d...

Understanding sperm DNA fragmentation

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. We greatly value the commentary by Dr. Gosalvez on the “Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios” by Agarwal et al. (1). The author initiated his well-written note with an overview of the structural and physiologic significance of sperm DNA on male repro...